Preimplantation genetic screening of embryos from couples experiencing repeated implantation failure
نویسندگان
چکیده
منابع مشابه
Frequency of chromosomal aneuploidy in high quality embryos from young couples using preimplantation genetic screening
BACKGROUND Selection of the best embryo for transfer is very important in assisted reproductive technology (ART). Using morphological assessment for this selection demonstrated that the correlation between embryo morphology and implantation potential is relatively weak. On the other hand, aneuploidy is a key genetic factor that can influence human reproductive success in ART. OBJECTIVE The ai...
متن کاملThe genetic screening of preimplantation embryos by comparative genomic hybridisation.
Comparative genomic hybridization (CGH) is an indirect DNA-based test which allows for the accurate analysis of aneuploidy involving any of the 24 types of chromosomes present (22 autosomes and the X and Y sex chromosomes). Traditionally, embryos have been screened using fluorescence in situ hybridization (FISH)--a technique that was limited in the number of chromosomes able to be identified in...
متن کاملthe relationship between hla-g gene polymorphisms and repeated implantation failure in infertile couples undergoing assisted reproductive technique repeated implantation failure in infertile couples undergoing assisted reproductive technique
hla-g is a tolerogenic molecule that expresses in cytotrophoblast cells and plays an important role in immune response suppression in maternal decidua. interactions between the extracellular domains of the hla-g protein with cell receptors of the immune system are well-known.this study investigated the association between hla-g gene polymorphism with repeated implantation failure (rif)...
متن کاملRepeated Implantation Failure
Successful embryo implantation is a process which requires both a synchronous development and interaction between hatched blastocyst and endometrium. The process of implantation as a scheme is presented in Pic. 1, where the diagram shows a preimplantation stage of embryo and some important factors thought to be necessary for uterine receptivity: COX-2 (cyclooxygenase-2), EGF (epidermal growth f...
متن کاملOnm-8: Recurrent Implantation Failure in IVF/ICSI Cycle
The success of assisted reproduction, although gradually increasing over the years, is still less than satisfactory. Many couples have benefited from this treatment; many have also been left frustrated following multiple failed attempts (Bulent Urman et al. 2005). Repeated implantation failure (RIF), defined as three or more failed IVF attempts or failure of IVF after cumula- Abstracts of the 5...
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ژورنال
عنوان ژورنال: Reproductive BioMedicine Online
سال: 2014
ISSN: 1472-6483
DOI: 10.1016/s1472-6483(14)50035-1